Key Takeaways

  • FAST mnemonic: Face drooping, Arm weakness, Speech difficulty, Time to call 911
  • Ischemic stroke (clot) may be treated with tPA (alteplase) if within 3-4.5 hours of symptom onset and no contraindications
  • tPA contraindications include recent surgery, active bleeding, history of intracranial hemorrhage, and uncontrolled hypertension
  • Hemorrhagic stroke requires blood pressure management and possible surgical intervention; tPA is contraindicated
  • Positioning for stroke patients: elevate HOB 30 degrees to reduce intracranial pressure; affected side up when lateral
Last updated: January 2026

Medical Emergencies: Stroke (CVA)

Stroke, also called cerebrovascular accident (CVA), is a medical emergency requiring immediate intervention. "Time is brain" - every minute without treatment results in the death of approximately 1.9 million neurons.

Types of Stroke

TypeMechanismPercentageTreatment
IschemicBlood clot blocks artery~87%tPA, mechanical thrombectomy
HemorrhagicBlood vessel ruptures~13%BP control, surgery
TIATemporary blockageN/APrevention of future stroke

FAST: Rapid Stroke Assessment

The FAST mnemonic enables anyone to quickly identify stroke symptoms:

F - Face Drooping

  • Ask the person to smile
  • Is one side of the face drooping or numb?
  • Look for uneven smile

A - Arm Weakness

  • Ask the person to raise both arms
  • Does one arm drift downward?
  • Is there weakness or numbness on one side?

S - Speech Difficulty

  • Ask the person to repeat a simple phrase
  • Is speech slurred or strange?
  • Is the person unable to speak or hard to understand?

T - Time to Call 911

  • If ANY of these symptoms are present, call 911 immediately
  • Note the time symptoms started (critical for treatment decisions)
  • "Last known well" time determines tPA eligibility

Additional Stroke Signs and Symptoms

Beyond FAST, watch for:

  • Sudden severe headache ("worst headache of my life" suggests hemorrhagic)
  • Sudden confusion
  • Trouble seeing in one or both eyes
  • Sudden trouble walking, dizziness, loss of balance
  • Sudden numbness on one side of body

Ischemic vs. Hemorrhagic Stroke Signs

FeatureIschemic StrokeHemorrhagic Stroke
OnsetCan be gradualSudden, severe
HeadacheUsually absentSevere, "thunderclap"
LOC ChangesMay be subtleOften profound
VomitingUncommonCommon
Neck StiffnessAbsentMay be present (SAH)

Diagnostic Workup

Immediate Imaging:

  • CT scan without contrast - First-line to rule out hemorrhage
  • Must be completed within 25 minutes of arrival
  • Hemorrhagic stroke appears bright white on CT
  • Ischemic stroke may not show changes initially

Additional Tests:

  • Blood glucose (hypoglycemia can mimic stroke)
  • CBC, coagulation studies (PT/INR, aPTT)
  • Basic metabolic panel
  • ECG (atrial fibrillation is a stroke risk factor)
  • MRI (more sensitive for ischemic stroke)

Treatment of Ischemic Stroke

Thrombolytic Therapy (tPA/Alteplase)

Tissue Plasminogen Activator (tPA) dissolves clots and restores blood flow.

Eligibility Criteria:

  • Symptom onset within 3-4.5 hours (some protocols extend to 4.5 hours)
  • CT confirms no hemorrhage
  • Measurable neurological deficit
  • Age 18 or older

Contraindications (Do NOT give tPA if):

Absolute Contraindications
Active internal bleeding
History of intracranial hemorrhage
Recent intracranial/spinal surgery (within 3 months)
Known intracranial neoplasm or AVM
Uncontrolled hypertension (SBP > 185 or DBP > 110)
Current anticoagulant use with INR > 1.7
Platelet count < 100,000

Nursing Considerations During tPA:

  • Strict blood pressure monitoring (every 15 min for 2 hours, then every 30 min for 6 hours)
  • Neuro checks every 15 minutes during infusion
  • NO anticoagulants or antiplatelets for 24 hours
  • Watch for bleeding (intracranial, GI, from puncture sites)
  • Do NOT place Foley, NG tube, or arterial lines during/immediately after infusion

Mechanical Thrombectomy

  • Catheter-based clot removal
  • For large vessel occlusions
  • Can extend treatment window to 24 hours in select patients
  • Used alone or with tPA

Treatment of Hemorrhagic Stroke

tPA is CONTRAINDICATED in hemorrhagic stroke - it would worsen bleeding.

Treatment Goals:

  1. Blood pressure management - Lower gradually to prevent rebleeding
    • Target varies by type and severity
    • Typically maintain SBP < 140-160 mmHg
  2. Reverse anticoagulation if applicable
    • Vitamin K for warfarin
    • Protamine for heparin
  3. Surgical intervention for large bleeds
    • Craniotomy for hematoma evacuation
    • Ventriculostomy for hydrocephalus

Nursing Care for Stroke Patients

Positioning

  • Elevate HOB 30 degrees to reduce intracranial pressure
  • When turning, affected side up (protects weakened side)
  • Avoid neck flexion (impedes venous drainage)

Neurological Monitoring

  • Use NIH Stroke Scale for standardized assessment
  • Document baseline and compare frequently
  • Report any deterioration immediately

Swallowing Assessment

  • NPO until swallow evaluation (dysphagia is common)
  • Bedside swallow screen before any oral intake
  • Speech therapy consult for formal evaluation
  • Aspiration precautions if dysphagia present

Preventing Complications

  • DVT prophylaxis (SCDs, anticoagulation when safe)
  • Early mobilization when stable
  • Skin integrity monitoring
  • Fall precautions

Time Windows in Stroke Care

BenchmarkTarget Time
Door to physician10 minutes
Door to CT completion25 minutes
Door to CT interpretation45 minutes
Door to tPA administration60 minutes

Exam Tip: For NCLEX, remember "Last known well" not "symptom discovery time" determines tPA eligibility. If a patient wakes with symptoms, the last known well time is when they went to sleep.


Key Points for the NCLEX

  • FAST is the rapid assessment tool for stroke
  • Ischemic stroke = clot = may receive tPA (if within window and no contraindications)
  • Hemorrhagic stroke = bleed = NO tPA (would worsen bleeding)
  • CT scan without contrast is first-line imaging to differentiate types
  • NPO until swallow evaluation is complete
  • Elevated HOB 30 degrees reduces intracranial pressure
  • "Time is brain" - rapid intervention improves outcomes
Test Your Knowledge

A patient arrives at the emergency department with left-sided weakness and slurred speech that began 2 hours ago. Which diagnostic test is the priority?

A
B
C
D
Test Your Knowledge

A patient with suspected ischemic stroke has a blood pressure of 200/115 mmHg. Which action should the nurse anticipate before tPA administration?

A
B
C
D
Test Your Knowledge

The nurse is caring for a patient who received tPA 30 minutes ago. The patient suddenly develops a severe headache and decreasing level of consciousness. What is the priority action?

A
B
C
D