Key Takeaways

  • Breast cancer screening: Mammograms start at age 40 (may begin at 50 depending on guidelines), performed annually or biannually based on risk assessment
  • Cervical cancer screening: Pap smears begin at age 21; every 3 years (21-29), every 5 years with HPV co-testing (30-65), or every 3 years without HPV testing
  • Colorectal cancer screening: Colonoscopy or alternative begins at age 45; if normal, colonoscopy repeated every 10 years; annual stool tests are an alternative
  • Blood pressure screening should occur at every healthcare visit for all adults; hypertension threshold is 130/80 mmHg or higher
  • Lipid screening begins at age 20 for average-risk adults, earlier if risk factors present; fasting lipid panel every 4-6 years
Last updated: January 2026

Health Screening Overview

Health screening detects disease before symptoms appear, enabling early intervention and improved outcomes. Nurses educate clients about recommended screenings and help ensure access to preventive care.


Principles of Screening

Effective screening programs should:

  • Detect conditions where early treatment improves outcomes
  • Use tests that are reliable, valid, and acceptable to patients
  • Be cost-effective at the population level
  • Have treatment available for detected conditions

Cancer Screening Guidelines

Breast Cancer Screening

Age/RiskRecommendation
Average risk, 40-44Option to begin annual mammography
Average risk, 45-54Annual mammography
Average risk, 55+Annual or biennial mammography
High riskEarlier screening, may include MRI

High-risk factors:

  • BRCA1/BRCA2 gene mutations
  • Personal history of breast cancer
  • Strong family history (first-degree relatives)
  • Previous chest radiation (e.g., Hodgkin lymphoma treatment)

Clinical Breast Exam: Recommended periodically; patient should know own breasts and report changes.

Breast Self-Awareness: Women should be familiar with how their breasts normally look and feel and report changes promptly.

Cervical Cancer Screening

AgeRecommendation
<21 yearsNo screening
21-29 yearsPap smear every 3 years
30-65 yearsPap + HPV co-testing every 5 years (preferred) OR Pap alone every 3 years
>65 yearsMay discontinue if adequate prior screening
Post-hysterectomyNo screening if cervix removed for benign reasons

HPV Vaccination: Recommended at age 11-12 (can start at 9); catch-up through age 26.

Key Point: Cervical cancer screening begins at 21 regardless of sexual activity. HPV testing is not recommended before age 30 as a primary screen.

Colorectal Cancer Screening

MethodFrequency
ColonoscopyEvery 10 years (gold standard)
FIT (Fecal Immunochemical Test)Annually
Stool DNA test (Cologuard)Every 1-3 years
CT colonographyEvery 5 years
Flexible sigmoidoscopyEvery 5 years

Who to Screen:

  • Average risk: Begin at age 45
  • High risk: Earlier screening (personal/family history, IBD, certain genetic syndromes)

If FIT is positive: Colonoscopy is required regardless of any prior colonoscopy.

Lung Cancer Screening

Who qualifies:

  • Age 50-80 years
  • 20+ pack-year smoking history
  • Current smoker OR quit within past 15 years

Method: Annual low-dose CT (LDCT)

Discontinue when:

  • Has not smoked for 15+ years, OR
  • Develops health problem limiting life expectancy or willingness to have treatment

Prostate Cancer Screening

Recommendation: Shared decision-making between patient and provider

AgeGuidance
50-69Discuss pros/cons of PSA testing
<50Consider earlier for high-risk (African American, family history)
>70Generally not recommended

Key Point: Routine PSA screening is controversial due to overdiagnosis; emphasize informed decision-making.

Skin Cancer Screening

  • No routine screening recommendation for general population
  • Patients should perform self-exams and report changes
  • Clinical skin exam for high-risk individuals
  • Use ABCDE for melanoma recognition:
    • Asymmetry
    • Border irregularity
    • Color variation
    • Diameter >6 mm
    • Evolving (changing)

Cardiovascular Screening

Blood Pressure

CategorySystolicDiastolic
Normal<120<80
Elevated120-129<80
Stage 1 HTN130-13980-89
Stage 2 HTN≥140≥90

Screening: At every healthcare visit for all adults.

Lipid Screening

When to begin: Age 20 for average-risk adults

Frequency: Every 4-6 years if normal; more often if risk factors

ComponentDesirable Level
Total Cholesterol<200 mg/dL
LDL ("bad")<100 mg/dL
HDL ("good")>40 mg/dL (men), >50 mg/dL (women)
Triglycerides<150 mg/dL

Diabetes Screening

Who to screen:

  • All adults age 35+ (every 3 years if normal)
  • Earlier if overweight/obese with risk factors
  • All adults with hypertension

Methods:

  • Fasting plasma glucose (FPG)
  • HbA1c
  • 2-hour oral glucose tolerance test (OGTT)
TestNormalPrediabetesDiabetes
FPG<100 mg/dL100-125≥126
HbA1c<5.7%5.7-6.4%≥6.5%

Other Important Screenings

Osteoporosis

DEXA Scan Recommendations:

  • Women age 65+
  • Men age 70+
  • Earlier if risk factors present (low body weight, steroid use, smoking, prior fracture)

Depression

Screen all adults, especially:

  • Pregnant and postpartum women
  • Chronic disease patients
  • Adolescents

Tools: PHQ-2 (initial), PHQ-9 (full assessment)

Sexually Transmitted Infections

PopulationScreening
Sexually active women <25Annual chlamydia and gonorrhea
Pregnant womenSyphilis, HIV, Hep B at first prenatal; others based on risk
MSM (men who have sex with men)At least annual HIV, syphilis, chlamydia, gonorrhea
HIV-positive individualsAnnual screening for STIs

Hepatitis C

Who to screen:

  • All adults age 18-79 (at least once)
  • Anyone with risk factors (IV drug use, blood transfusion before 1992)

Preventive Care Summary by Age

Age GroupKey Screenings
18-39BP, lipids (age 20+), STIs if sexually active, depression
40-49Add mammography (age 40), diabetes (age 35+)
50-64Add colonoscopy (age 45+), lung cancer if smoker
65+Add DEXA, consider discontinuing some screenings

Exam Tips

  • Know when to START each screening (age triggers)
  • Know frequency of repeat screenings
  • Recognize high-risk factors that warrant earlier screening
  • Understand shared decision-making for prostate cancer screening
  • Remember colorectal cancer screening now starts at 45 (updated from 50)
  • Cervical cancer screening starts at 21 regardless of sexual activity
Test Your Knowledge

A 48-year-old female asks the nurse about cervical cancer screening. She had a Pap smear and HPV test last year, both negative. When is her next screening due?

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Test Your Knowledge

At what age should colorectal cancer screening begin for an average-risk adult?

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D
Test Your Knowledge

A nurse is teaching a 55-year-old man about prostate cancer screening. Which statement by the nurse is most accurate?

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B
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D