Key Takeaways

  • COPD patients: target SpO2 88-92% to avoid suppressing hypoxic drive
  • Continuous bubbling in chest tube water seal indicates an air leak
  • Active TB requires airborne precautions with negative pressure room and N95 respirators
  • PE presents with sudden dyspnea, pleuritic chest pain, and hypoxia
  • Asthma is reversible; COPD is irreversible airway obstruction
Last updated: January 2026

Respiratory Alterations

Respiratory conditions can rapidly become life-threatening. LPN/VNs must recognize respiratory distress, understand common respiratory disorders, and implement appropriate interventions.

Signs of Respiratory Distress

SignDescription
DyspneaShortness of breath, labored breathing
TachypneaRespiratory rate > 20/min
Use of Accessory MusclesNeck, intercostal, abdominal muscles working to breathe
Nasal FlaringWidening of nostrils with each breath
RetractionsVisible pulling in of chest wall
CyanosisBlue discoloration of lips, nail beds (late sign)
Altered Mental StatusConfusion, restlessness (sign of hypoxia)
Abnormal Breath SoundsCrackles, wheezes, diminished sounds

Chronic Obstructive Pulmonary Disease (COPD)

COPD includes chronic bronchitis and emphysema, characterized by irreversible airflow obstruction.

FeatureChronic BronchitisEmphysema
Nickname"Blue bloater""Pink puffer"
PathologyExcessive mucus, airway inflammationAlveolar destruction, loss of elasticity
CoughProductive, chronicMinimal
AppearanceCyanotic, overweightThin, barrel chest
DyspneaDuring exertionProgressive, at rest

COPD Management:

  • Bronchodilators: Short and long-acting (albuterol, tiotropium)
  • Corticosteroids: Inhaled for maintenance, systemic for exacerbations
  • Oxygen Therapy: Low-flow (1-2 L/min) to maintain SpO2 88-92%
  • Pulmonary Rehabilitation: Breathing exercises, energy conservation
  • Smoking Cessation: Most important intervention

COPD Oxygen Precaution:

  • Patients with chronic CO2 retention breathe based on hypoxic drive
  • High-flow oxygen may suppress respiratory drive
  • Use low-flow oxygen; maintain SpO2 88-92%

Asthma

Asthma is a reversible airway obstruction caused by inflammation, bronchoconstriction, and increased mucus production.

Asthma Triggers:

  • Allergens (dust, pollen, pet dander)
  • Respiratory infections
  • Exercise
  • Cold air
  • Irritants (smoke, chemicals)
  • Stress/emotions

Asthma Management:

CategoryMedicationsPurpose
Quick Relief (Rescue)SABA (albuterol)Acute bronchospasm relief
Controller (Maintenance)ICS (fluticasone), LABA (salmeterol), leukotriene modifiersPrevent attacks, reduce inflammation
Severe AttacksSystemic corticosteroids, epinephrineEmergency treatment

Peak Flow Monitoring:

  • Green zone (80-100% of personal best): Good control
  • Yellow zone (50-79%): Caution, use rescue inhaler
  • Red zone (< 50%): Medical alert, seek emergency care

Pneumonia

Pneumonia is an infection of the lung parenchyma causing consolidation.

Types:

TypeCausative AgentCharacteristics
Community-Acquired (CAP)Streptococcus pneumoniae, virusesDevelops outside healthcare setting
Hospital-Acquired (HAP)MRSA, PseudomonasDevelops 48+ hours after admission
AspirationMixed flora, anaerobesFrom aspiration of oral/gastric contents

Pneumonia Signs and Symptoms:

  • Fever, chills
  • Productive cough (may be rust-colored sputum)
  • Dyspnea, tachypnea
  • Chest pain (pleuritic)
  • Crackles, bronchial breath sounds
  • Elevated WBC

Nursing Interventions:

  • Administer antibiotics as ordered
  • Encourage coughing and deep breathing
  • Incentive spirometry
  • Adequate hydration (thins secretions)
  • Position for maximum lung expansion
  • Monitor oxygen saturation

Pulmonary Embolism (PE)

Pulmonary embolism occurs when a clot (usually from DVT) travels to the lungs.

Risk Factors (Virchow's Triad):

  1. Venous stasis: Immobility, surgery, long travel
  2. Vessel damage: Trauma, surgery
  3. Hypercoagulability: Cancer, pregnancy, clotting disorders

PE Signs and Symptoms:

  • Sudden dyspnea
  • Sharp, pleuritic chest pain
  • Tachycardia, tachypnea
  • Hypoxia
  • Anxiety, sense of impending doom
  • May have signs of DVT (unilateral leg swelling)

PE Management:

  • Oxygen therapy
  • Anticoagulation (heparin → warfarin or DOACs)
  • Thrombolytics in massive PE
  • IVC filter if anticoagulation contraindicated
  • Prevention: Early ambulation, SCDs, anticoagulation prophylaxis

Tuberculosis (TB)

TB is a bacterial infection (Mycobacterium tuberculosis) primarily affecting the lungs.

TB Transmission:

  • Airborne droplet nuclei
  • Requires prolonged close contact
  • Not spread by touching surfaces

Latent vs. Active TB:

FeatureLatent TBActive TB
SymptomsNoneNight sweats, weight loss, persistent cough, hemoptysis
InfectiousNoYes
Chest X-rayMay be normalOften abnormal
TreatmentINH for 6-9 monthsMulti-drug regimen for 6-12 months

TB Precautions:

  • Airborne isolation (negative pressure room)
  • N95 respirator for healthcare workers
  • Patient wears surgical mask during transport
  • Continue until three negative sputum AFB smears

Chest Tubes

Indications: Pneumothorax, hemothorax, pleural effusion, post-thoracic surgery

Chest Tube Care:

  • Keep drainage system below chest level
  • Maintain water seal (2 cm water)
  • Monitor for tidaling (normal fluctuation with respiration)
  • Continuous bubbling in water seal = air leak
  • Assess drainage color, amount (> 100 mL/hr is concerning)
  • Never clamp except briefly for troubleshooting or system change
  • Keep petroleum gauze at bedside (for accidental removal)
Test Your Knowledge

A patient with COPD is receiving oxygen therapy. What is the target oxygen saturation range for this patient?

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Test Your Knowledge

A patient with a chest tube has continuous bubbling in the water seal chamber. What does this indicate?

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Test Your Knowledge

What type of isolation precautions are required for a patient with active pulmonary tuberculosis?

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D