Key Takeaways

  • GCS of 8 or below = severe injury requiring airway protection
  • During seizures: protect from injury, time duration, position on side after
  • Increased ICP: elevate HOB 30 degrees, head midline, avoid activities that raise ICP
  • Stroke: BE FAST for recognition; tPA must be given within 4.5 hours for ischemic stroke
  • Kernig's and Brudzinski's signs indicate meningeal irritation (meningitis)
Last updated: January 2026

Neurological Alterations

Neurological conditions can dramatically affect patient function and quality of life. LPN/VNs must perform accurate neurological assessments and recognize changes that require immediate intervention.

Neurological Assessment

Level of Consciousness (LOC): LOC is the most sensitive indicator of neurological change.

LevelDescription
AlertAwake, oriented, responds appropriately
LethargicDrowsy but easily aroused
ObtundedDifficult to arouse, confused when awake
StuporousArouses only with vigorous stimulation
ComatoseUnresponsive to stimulation

Glasgow Coma Scale (GCS):

ResponseScore
Eye Opening
Spontaneous4
To voice3
To pain2
None1
Verbal Response
Oriented5
Confused4
Inappropriate words3
Incomprehensible sounds2
None1
Motor Response
Obeys commands6
Localizes pain5
Withdraws from pain4
Flexion (decorticate)3
Extension (decerebrate)2
None1

Total Score: 3-15 (3 = worst, 15 = best)

  • Severe injury: 3-8
  • Moderate injury: 9-12
  • Mild injury: 13-15

Pupil Assessment:

  • PERRLA: Pupils Equal, Round, Reactive to Light and Accommodation
  • Unequal pupils (anisocoria): May indicate increased ICP, herniation
  • Dilated, fixed pupil: Sign of brain herniation

Increased Intracranial Pressure (ICP)

Normal ICP: 5-15 mmHg

Causes:

  • Brain tumor, abscess
  • Traumatic brain injury
  • Stroke (hemorrhagic or large ischemic)
  • Hydrocephalus
  • Encephalitis, meningitis

Signs and Symptoms:

Early SignsLate Signs
Headache (worse in AM)Decreased LOC
Nausea/vomitingPupil changes (unilateral dilation)
Restlessness, confusionCushing's triad: bradycardia, hypertension, irregular respirations
Visual changesPosturing (decorticate → decerebrate)
Seizures

Nursing Interventions for Increased ICP:

  • Elevate HOB 30 degrees (promotes venous drainage)
  • Maintain head in midline (prevents jugular vein compression)
  • Avoid activities that increase ICP: coughing, straining, suctioning, Valsalva
  • Monitor neuro status frequently
  • Maintain quiet, calm environment
  • Administer osmotic diuretics (mannitol) as ordered

Stroke (Cerebrovascular Accident)

Types of Stroke:

TypeCauseTreatment Window
Ischemic (85%)Clot blocking blood flowtPA within 4.5 hours of symptom onset
Hemorrhagic (15%)Bleeding in brainControl bleeding, manage ICP

Stroke Warning Signs (BE FAST):

  • Balance: Sudden loss of balance
  • Eyes: Sudden vision changes
  • Face: Facial drooping
  • Arm: Arm weakness, drift
  • Speech: Slurred speech, difficulty speaking
  • Time: Time to call 911

Stroke Complications and Care:

ComplicationNursing Interventions
DysphagiaNPO until swallow evaluation; aspiration precautions
Hemiplegia/paresisROM exercises, positioning, mobility training
AphasiaUse simple communication, allow time, speech therapy
NeglectApproach from unaffected side, teach scanning
IncontinenceBladder training, toileting schedule
Emotional labilityProvide support, allow expression, consistency

Seizures

Types of Seizures:

TypeDescriptionCharacteristics
Generalized Tonic-ClonicWhole body involvementLoss of consciousness, rigidity (tonic), jerking (clonic)
AbsenceBrief loss of awarenessStaring, may not remember episode
Focal (Partial)One area of brainMay or may not lose consciousness
Status EpilepticusContinuous or rapidly recurring seizuresMedical emergency (> 5 minutes)

Seizure Management:

  • During seizure:

    • Stay with patient
    • Protect from injury (clear area, don't restrain)
    • Turn to side if possible (after tonic-clonic phase)
    • Do NOT put anything in mouth
    • Time the seizure
    • Call for help if > 5 minutes or injury suspected
  • After seizure (postictal period):

    • Maintain airway, position for drainage
    • Reorient patient
    • Assess for injuries
    • Allow rest
    • Document: type, duration, body parts involved, aura, postictal state

Meningitis

Meningitis is inflammation of the meninges (membranes covering brain and spinal cord).

Types:

  • Bacterial: Most serious, requires immediate treatment
  • Viral: Usually less severe, supportive care
  • Fungal: Often in immunocompromised patients

Signs and Symptoms:

  • Fever, headache
  • Nuchal rigidity (stiff neck)
  • Photophobia
  • Altered mental status
  • Kernig's sign: Unable to straighten leg when hip flexed
  • Brudzinski's sign: Neck flexion causes hip/knee flexion

Meningitis Precautions:

  • Bacterial meningitis: Droplet precautions until 24 hours of antibiotic therapy
  • Private room, mask for close contact
  • Prophylaxis for close contacts may be ordered

Parkinson's Disease

Parkinson's disease is a progressive movement disorder caused by dopamine deficiency.

Cardinal Signs (TRAP):

  • Tremor: Resting tremor ("pill-rolling")
  • Rigidity: Muscle stiffness, "cogwheel" rigidity
  • Akinesia/Bradykinesia: Slow movement
  • Postural instability: Balance problems, shuffling gait

Nursing Considerations:

  • Medications must be given on time (levodopa has narrow window)
  • Fall prevention (shuffling gait, balance issues)
  • Swallowing assessment (dysphagia risk)
  • Allow extra time for activities
  • Maintain mobility and independence as long as possible
Test Your Knowledge

A patient's Glasgow Coma Scale score drops from 12 to 8. What does this indicate?

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Test Your Knowledge

During a seizure, what is the priority nursing action?

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D
Test Your Knowledge

A patient with suspected increased ICP should be positioned with:

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B
C
D