Key Takeaways

  • Transmission-Based Precautions add to Standard Precautions for specific infections
  • Contact Precautions: gown and gloves for MRSA, C. diff, scabies
  • Droplet Precautions: surgical mask within 6 feet for flu, COVID, pertussis
  • Airborne Precautions: N95 in negative pressure room for TB, measles, chickenpox
  • C. diff requires soap and water - ABHR does not kill the spores
Last updated: January 2026

Transmission-Based Precautions

Transmission-Based Precautions are additional measures used for patients with known or suspected infections that require more than Standard Precautions alone. They are based on how the infection spreads.

Three Types of Transmission-Based Precautions

TypeHow Infection SpreadsExamples of Diseases
ContactDirect or indirect contactMRSA, C. diff, scabies, lice
DropletLarge respiratory droplets (>5 microns)Flu, COVID-19, pertussis, mumps
AirborneTiny particles (<5 microns) that floatTB, measles, chickenpox, disseminated shingles

Contact Precautions

Used when infection spreads by touching:

RequirementSpecifics
RoomPrivate room preferred; cohort if needed
PPEGown and gloves for all contact
EquipmentDedicated (don't share between patients)
TransportLimit; contain infected areas
SignPosted on door

Common Contact Precaution infections:

  • MRSA (Methicillin-resistant Staph aureus)
  • VRE (Vancomycin-resistant Enterococcus)
  • C. difficile (C. diff)
  • Scabies
  • Lice
  • Wound infections with drainage

Droplet Precautions

Used when infection spreads by large respiratory droplets:

RequirementSpecifics
RoomPrivate room preferred; cohort if needed
PPESurgical mask within 6 feet of patient
TransportPatient wears mask if leaving room
DistanceMaintain 6 feet if possible
SignPosted on door

Common Droplet Precaution infections:

  • Influenza (flu)
  • COVID-19 (may also require airborne for some procedures)
  • Pertussis (whooping cough)
  • Mumps
  • Rubella
  • Strep throat (Group A Strep)

Airborne Precautions

Used when tiny particles remain suspended in air:

RequirementSpecifics
RoomAirborne Infection Isolation Room (AIIR) with negative pressure
PPEN95 respirator or PAPR
DoorKeep closed at all times
TransportPatient wears mask; limit transport
Fit testingRequired annually for N95
SignPosted on door

Common Airborne Precaution infections:

  • Tuberculosis (TB)
  • Measles
  • Chickenpox (Varicella)
  • Disseminated shingles (Herpes Zoster)
  • COVID-19 (for aerosol-generating procedures)

Special Considerations

C. difficile (C. diff):

  • Contact precautions
  • Soap and water for hand hygiene (ABHR doesn't kill spores)
  • Bleach-based disinfectant for cleaning

MRSA:

  • Contact precautions
  • May be in nares, wounds, or urine
  • Strict hand hygiene between patients

COVID-19:

  • Droplet + Contact precautions for standard care
  • Airborne precautions for aerosol-generating procedures
  • N95 or higher respirator

Isolation Room Requirements

Precaution TypeRoom Features
ContactPrivate room preferred
DropletPrivate room preferred
AirborneNegative pressure room with 6-12 air changes/hour

CNA Responsibilities in Isolation

ResponsibilityAction
Check signsKnow which precautions before entering
Don PPEProper sequence before entry
Provide careFollow all precaution requirements
Doff PPEProper sequence in room or anteroom
Hand hygieneImmediately after leaving room
ReportIf you lack proper equipment

Cohorting Patients

When private rooms are not available:

  • Cohort = grouping patients with same infection
  • Same PPE requirements apply
  • Change gloves and hand hygiene between patients
  • Avoid cross-contamination

Isolation and Patient Well-being

Isolation can negatively affect patients:

  • Loneliness and depression
  • Less frequent staff visits
  • Feeling "contagious" or "dirty"

CNA support:

  • Visit as often as safely possible
  • Provide emotional support
  • Explain why precautions are needed
  • Ensure call light is accessible
  • Report psychological concerns to nurse
Test Your Knowledge

A patient with tuberculosis (TB) requires which type of precautions?

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B
C
D
Test Your Knowledge

What type of mask is required for Airborne Precautions?

A
B
C
D
Test Your Knowledge

Which infection requires Contact Precautions AND soap and water hand hygiene (not ABHR)?

A
B
C
D